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BALTIMORE (AP) -

Nelson Cruz celebrated his Orioles debut by hitting a tiebreaking home run in the seventh inning and Baltimore beat Jon Lester and the defending World Series champion Boston Red Sox 2-1 Monday before an appreciative sellout crowd on opening day.

Signed as a free agent in February, Cruz lined a solo shot into the left-field seats to put the Orioles ahead. He hit 27 homers last year with Texas during a season marred by a 50-game suspension from Major League Baseball in the Biogenesis drug scandal.

After missing two seasons recovering from knee surgery, Boston's Grady Sizemore marked his return from a 922-day absence with a second-inning single. He also hit his first home run since July 15, 2011.

Zach Britton (1-0) got the win with two scoreless innings of relief and Tommy Hunter worked the ninth for his first save. Lester (0-1) gave up two runs in seven innings.

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